October 20, 2012

Chewing Gum Developed For Motion Sickness

Feelings of nausea hit the stomach. The head is feeling dizzy by the second. These are just a few symptoms of motion sickness. Motion sickness can hit people of ages and background, especially pregnant females and young children. Recently, there have been more and more studies that have investigated different options to help combat motion sickness. In particular, a new study publicized by the American Association of Pharmaceutical Sciences (AAPS) discovered that a new type of chewing gum could help suppress motion sickness.

Based on the findings of the study, researchers believe that the novel prototype has a number of benefits compared to normal oral, solid dosage forms. Sadatrezaei developed the gum along with researchers from the Islamic Azad University School of Pharmaceutical Sciences in Iran. It is believed to have the ability to boost patient compliance and can be absorbed more quickly through the cheek; these two factors will help decrease motion sickness at a faster rate. With a sensory panel, the scientists were able to examine faster absorption with the buccal cavity in the mouth that lead to a quicker response against motion sickness. The findings were recently presented at the 2012 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition that was help in Chicago this past week.

“The main challenge in delivering drugs through chewing gum is masking the bitter taste of its active ingredient,” commented lead researcher Mohsen Sadatrezaei of RoshaDarou Co. in a prepared statement. “We have formulated dimenhydrinate as chewing gum with acceptable taste and sensory attributes. Dimenhydrinate is among the best drug candidates for treatment of motion sickness, providing a comfortable and acceptable drug delivery.”

Participants in the study also rated the gum based on its easiness to chew and the bitterness. The researchers believe that the final dimenhydrinate chewing product can be commercialized. As well, the results of the study show that chewing gum can combine other active ingredients.

The findings are particularly important to the segment of the population that is affected easily by motion sickness. According to the AAPS, approximately 33 percent of the population can easily be affected by motion sickness in mild conditions while 66 percent are impacted by motion sickness in more intense situations. The U.S. National Library of Medicine also reports that motion sickness can occur when people are traveling with different forms of transport like airplane, car, train, and boats. It can cause people to feel queasy or start to have cold sweats. Other symptoms of motion sickness include dizziness and vomiting.

For individuals who suffer from motion sickness, the U.S. Centers for Disease Control and Prevention (CDC) provide a list of preventive measures for people who are traveling. For one, individuals should be cognizant of situations that may trigger feelings of motion sickness. When possible, it is best to seek an optimum seating position, whether that be sitting in the front seat of a bus or deciding to drive a car instead of sitting in it. For some people, increasing distractions or sensory input can help people feel calm. Lastly, while there is not much scientific data on this particular topic, individuals can seek acupuncture to help limit or treat nausea.

Image Credit: Photos.com

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