fresh grapefruit fruit with cut
December 11, 2012

Grapefruit and Medicine Do Not Mix

If you are one of those people who loves to eat grapefruit or drink grapefruit juice first thing in the morning, then you should know that it can be harmful to do so if you are currently taking certain drugs.

Although it has always been known that certain drugs and grapefruit negatively react, new studies actually show that the risk of danger is much bigger now than it was originally believed to be previously. This is mainly because people have failed to realize that there is a much wider array of medications available in today’s day and age compared to before. Therefore, it only makes sense that the amount of potential interactions has skyrocketed, as well.

In fact, things have gone so completely out of hand that grapefruit can sometimes make drugs more potent, completely inactive or extremely dangerous, depending on each individual case. Because of this, it would be highly advisable not to combine grapefruit with drugs at all.

Here is an incomplete list of drugs that have shown to react negatively to grapefruit products from the Mayo clinic.

These interactions tend to be greater in people who are 50 years old and up, though, because they seem to drink more grapefruit juice, in general, and consume more medication at the same time.

Overall, there is a long list of drugs that could make grapefruit react in an unwanted manner, some of which are very popular and some of which a lot of people take every single day, including antibiotics and cardiac drugs. Because of this, it would be vital to know that these interactions can exist before drinking grapefruit juice while on medication.

In a nutshell, grapefruit juice tends to block special enzymes found in the small intestine’s walls and destroys a lot of medications by preventing their absorption in the body. Because of this, the body might not get the amount of drugs that it is suppose to ingest. In other cases, the enzymes’ actions get blocked and too much of the drugs get into the body, unintentionally increasing the person’s blood levels. This could then result in very dangerous side effects.

Now, this doesn’t necessarily mean that you have to avoid drinking grapefruit juice forever. It simply means that you shouldn’t drink your medicine if you plan on drinking grapefruit juice or have just drank some. The least you can do is wait for the juice to get through your stomach before drinking your medications.

So, is there any indication on the amount of grapefruit juice that needs to be avoided? Well, to be honest, this study isn’t exactly perfect, so there is no exact amount on how much grapefruit juice you should or should not be drinking. In a nutshell, you simply have to separate what you eat and what you drink from when you drink your medications and at least give around six hours leeway for the juice to get out of your stomach. After all, the majority of problems usually take place before those six hours are up.

Overall, grapefruit juice is still known to have a lot of beneficial compounds that can effectively reduce atherosclerosis and the risk of cancer. As such, it is safe to say that this juice is a classic nutraceutical. However, if you are taking certain medications, it might be best to avoid drinking this juice for now since it can interact with various medications.

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